Cannabis HPLC Analyzer Accuracy
We take the accuracy of our cannabis HPLC analyzer, validation of test methods, and sampling protocols extremely seriously. With our instrument, you will be operating like a certified professional lab. In fact, you can see a comparison of our results to other ca. 140 labs in North America in a cannabis laboratory quality assurance comparison study here.
Detection limit of most cannabinoids is 0.03ug/mL (30ppb, 0.000003%)
NRC Hemp – Certified Reference Material Study
|Measured Cannabinoids||CTInstruments HPLC||Mean value of 140 labs across North America||National Institute of Science and Technology (NIST)|
Lower Limit of Quantification (LLOQ)
The lower limit of quantification (LLOQ) is the lowest amount of a cannabinoid in a sample that can be quantitatively determined with suitable precision and accuracy using the corresponding method and dilution rates. All values below this threshold are reported as less than LLOQ.
|Compound||Plant LLOQ (%,w/w)||High % Concentrate LLOQ (%,w/w)|
Reproducibility of results
Below are results of measuring a typical hemp sample, followed by an image of stacked 3 consecutive measurements. There are two observations from this measurement:
- The retention times are consistent and repeatable, giving the confidence in the ability to correctly identify the correct cannabinoids.
- The measured concentrations are very repeatable as indicated by height/area of each peak. The calculated relative standard deviation (RSD) in this case ranges from 1.19% to 1.70%, while for cannabinoids with very low concentrations manifested as very small peaks (in this sample CBN, d9-THC, and d9-THCA) the calculated RSD ranges from 4.62% to 5.63%. In case of need to further refine the latter 3 compounds and improve both accuracy and RSD, the sample would simply be less diluted resulting in higher peaks for these 3 compounds.