Cannabis HPLC Analyzer with Autosampler

Our HPLC with Autosampler

Award-winning, simple-to-use HPLC suitable for those without prior laboratory experience or science background, as well as professionals & commercial labs alike. Addition of our plug&play autosampler makes the HPLC suitable for high throughput commercial analyses of cannabis samples.

No PhD? No problem! We teach you everything.

HPLC = high performance liquid chromatography

  • convenience – do in-house analyses on a commercial scale; suitable for commercial labs to expand their capacity
  • analyze plant, extracts, edibles, beverages
  • test 13 major cannabinoids and more…
  • easy to follow instructions
  • reliable performance
  • long-term use
  • accurate results
  • compact size
  • optimized for cost and throughput

Total THC, Total CBD, Total CBG, d9-THC, d8-THC, THCa, THCV, THCVa, CBD, CBDa, CBDV, CBG, CBGa, CBC, CBN, CBL

Cannabis HPLC with Autosampler from CTInstruments Cannabis Testing

HPLC Features

  • Reciprocating Pump
  • UV/VIS Detector
  • Rheodyne 7725i Injector
  • Temperature-controlled Column Compartment
  • CTI HPLC Software
  • Software available both as local and cloud-hosted version

HPLC Specifications

  • Flow Rate 0.001 – 5mL/min
  • Max Pressure 6,300 psi
  • Flow Accuracy ≤±1%
  • Flow Precision RSD <0.1%
  • Qualitative Repeatability
  • RSD ≤0.2% (Naphthalene/Methanol standards)
  • Quantitative Repeatability RSD ≤0.5% (Naphthalene/Methanol standards)
  • Wavelength Range 180 – 680nm
  • Spectrum Bandwidth 8nm
  • Wavelength Accuracy ±1nm
  • Wavelength Precision Below 0.1nm
  • Noise ≤0.25X10-5AU

HPLC Column Specifications

  • Column Type C18, SS body
  • Dimensions 150×4.6mm
  • Packing 5μm particles
  • Guard Column C18

Autosampler Specifications

  • Plug & play design – can be added to HPLC at any time
  • 45 samples tray
  • Robust and reliable design

Included in the HPLC Package:

Everything you need to use it without having to do any development work. All quality control measures and sample management included.

  1. HPLC with temperature-controlled column compartment
  2. 150mm C18 column with included guard column holder and cartridge
  3. Accessories for installation and maintenance
  4. 45 sample autosampler
  5. Intuitive HPLC software
  6. Autosampler management software
  7. Peak Auto Detection
  8.  Proven, tested, and validated test methods
  9. Calibration curves
  10. Quality control and Calibration Validation log
  11. Sample receiving log
  12. Customer log
  13. Maintenance log
  14. Sample Preparation Protocols – tested and validated for various sample types
  15. Standard Operating Procedure (SOP)
  16. Customizable Reporting System (Managed in MS Excel)
  17. Easy-to-follow Instructions
  18. Manual
  19. Training
  20. Technical Support


Optional Starter Kit contains everything you need to get going right away. There are 29 items in the starter kit (major items listed below).

  1. Commercial calibration standards – d9-THC, CBD, Benzoic Acid Certified HPLC Calibration Standards, Standard containing 12 cannabinoids.
  2. 1L HPLC buffer
  3. 1L HPLC grade Methanol
  4. 1L HPLC grade Acetonitrile
  5. 1L HPLC grade Water
  6. 3x100mL HPLC mobile phase bottle
  7. 1x500mL HPLC mobile phase bottle
  8. 100uL Hamilton microsyringe
  9. 2.5mL Hamilton microsyringe
  10. 2x5mL calibrated volumetric pipette
  11. 15mL calibrated volumetric pipette
  12. 20mL calibrated volumetric pipette
  13. 100mL calibrated volumetric flask
  14. Glassware
  15. 100×1.8mL autosampler vials with PTFE/silicone cap
  16. 100x16mL glass vial for extraction
  17. Precision digital analytical scale (0.1 mg accuracy)
  18. Nitrile gloves, labels

We take accuracy of our instruments, validation of test methods, and sampling protocols extremely seriously. With our instrument, you will be operating like a certified professional lab. In fact, you can see a comparison of our results to other ca. 140 labs in North America in a quality control comparison study here.


Here is more info:

Detection limit of most cannabinoids is 0.03ug/mL (30ppb, 0.000003%)

Lower Limit of Quantification (LLOQ)

The lower limit of quantification (LLOQ) is the lowest amount of a cannabinoid in a sample that can be quantitatively determined with suitable precision and accuracy using the corresponding method and dilution rates. All values below this threshold are reported as NR – None Reported.

CompoundPlant LLOQ (%,w/w)High % Concentrate LLOQ (%,w/w)
Note: LLOQ values are dependent on sample dilution. These are values for standard methods but can be modified with dilution in case of need.


Reproducibility of results

Below are results of consecutive measurements of cannabinoids commercial standard at 5% mark of the calibration curve.

As seen in the image, the relative standard deviation (RSD) is ranging from 0.37% to 1.23% for these cannabinoids. We can also observe RSD of retention times ranging from 0.22% to 0.27%.


Cannabis Testing Simplified Autosampler RSD

Cannabis HPLC Analyzer with Autosampler RSD

Comparison of Cannabis HPLC Analyzers

Our HPLCShimadzu Cannabis Potency Analyzer
Agilent 1220 Infinity II LC System
# of cannabinoids131111
# of terpenes28nonenone
Type of sample testedanyanyany
# of samples per 8 hours364848
Ease of usebeginneradvanced useradvanced user
Type of instrumentcommercialcommercialcommercial
Cannabis industry expertiseexcellentexcellentexcellent
Cannabinoids Testing Process Flow Chart

Cannabinoids Testing Process Flow Chart

We try to expand the financing options to help our customers acquire the instrument.


  1. Direct purchase – contact us to get a quote. We accept cryptocurrency transactions.
  2. Financing – we partner with financing firms in the cannabis industry to help our customers acquire the instrument. Learn more here.
  3. Rental – contact us for rental terms.

Contact us to get a quote or with any questions.


[email protected]