Cannabis HPLC Analyzer

Curious about our cannabis HPLC?

Award-winning, simple-to-use HPLC suitable for those without prior laboratory experience or science background, as well as professionals & commercial labs alike.

No PhD? No problem! We teach you everything.

HPLC = high performance liquid chromatography

  • convenience – do in-house analyses
  • analyze plant, extracts, edibles, beverages
  • test 13 major cannabinoids and more…
  • easy to follow instructions
  • reliable performance
  • long-term use
  • accurate results
  • compact size (18x9x10.5 inch)
  • optimized for cost at $5 ~ $10/test

Total THC, Total CBD, Total CBG, d9-THC, d8-THC, THCa, THCV, THCVa, CBD, CBDa, CBDV, CBG, CBGa, CBC, CBN, CBL

2020 Commercial Cannabis Award - instagram

HPLC Features

  • Reciprocating Pump
  • UV/VIS Detector
  • Rheodyne 7725i Injector
  • Temperature-controlled Column Compartment
  • CTI HPLC Software

HPLC Specifications

  • Flow Rate 0.001 – 5mL/min
  • Max Pressure 6,300 psi
  • Flow Accuracy ≤±1%
  • Flow Precision RSD <0.1%
  • Qualitative Repeatability
  • RSD ≤0.2% (Naphthalene/Methanol standards)
  • Quantitative Repeatability RSD ≤0.5% (Naphthalene/Methanol standards)
  • Wavelength Range 180 – 680nm
  • Spectrum Bandwidth 8nm
  • Wavelength Accuracy ±1nm
  • Wavelength Precision Below 0.1nm
  • Noise ≤0.25X10-5AU

HPLC Column Specifications

  • Column Type C18, SS body
  • Dimensions 150×4.6mm
  • Packing 5μm particles
  • Guard Column C18

Included in the HPLC Package:

Everything you need to use it without having to do any development work. All quality control measures and sample management included.

  1. HPLC with temperature-controlled column compartment
  2. 150mm C18 column with included guard column holder and cartridge
  3. Accessories for installation and maintenance
  4. Intuitive HPLC software
  5. Peak Auto Detection
  6.  Proven, tested, and validated test methods
  7. Calibration curves
  8. Quality control and Calibration Validation log
  9. Sample receiving log
  10. Customer log
  11. Maintenance log
  12. Sample Preparation Protocols – tested and validated for various sample types
  13. Standard Operating Procedure (SOP)
  14. Customizable Reporting System (Managed in MS Excel)
  15. Easy-to-follow Instructions
  16. Manual
  17. Training
  18. Technical Support

 

Optional Starter Kit contains everything you need to get going right away. There are 29 items in the starter kit (major items listed below).

  1. Commercial calibration standards – d9-THC, CBD, Benzoic Acid Certified HPLC Calibration Standards, Standard containing 12 cannabinoids.
  2. 1L HPLC buffer
  3. 1L HPLC grade Methanol
  4. 1L HPLC grade Acetonitrile
  5. 1L HPLC grade Water
  6. 3x100mL HPLC mobile phase bottle
  7. 1x500mL HPLC mobile phase bottle
  8. 100uL Hamilton microsyringe
  9. 2.5mL Hamilton microsyringe
  10. 2x5mL calibrated volumetric pipette
  11. 15mL calibrated volumetric pipette
  12. 20mL calibrated volumetric pipette
  13. 100mL calibrated volumetric flask
  14. Glassware
  15. 100×1.8mL autosampler vials with PTFE/silicone cap
  16. 100x16mL glass vial for extraction
  17. Precision digital analytical scale (0.1 mg accuracy)
  18. Nitrile gloves, labels

We take accuracy of our instruments, validation of test methods, and sampling protocols extremely seriously. With our instrument, you will be operating like a certified professional lab. In fact, you can see a comparison of our results to other ca. 140 labs in North America in a quality control comparison study here.

 

NRC Hemp – Certified Reference Material Study

Measured CannabinoidsCTInstruments HPLCMean value of 140 labs across North AmericaNational Institute of Science and Technology (NIST)
d9-THC0.0467%0.0372%0.0415%
THCA0.1067%0.0911%0.109%
CBD0.5367%0.517%0.584%
CBDA1.607%1.330%1.560%
Total THC0.1433%0.111%0.137%
Total CBD1.947%1.700%1.970%

Detection limit of most cannabinoids is 0.03ug/mL (30ppb, 0.000003%)

Lower Limit of Quantification (LLOQ)

The lower limit of quantification (LLOQ) is the lowest amount of a cannabinoid in a sample that can be quantitatively determined with suitable precision and accuracy using the corresponding method and dilution rates. All values below this threshold are reported as NR – None Reported.

CompoundPlant LLOQ (%,w/w)High % Concentrate LLOQ (%,w/w)
Δ9-THC0.030.04
Δ8-THC0.030.06
Δ9-THCA0.030.06
THCV0.030.04
CBD0.030.03
CBDA0.030.03
CBDV0.030.03
CBG0.030.03
CBGA0.030.03
CBN0.030.03
CBC0.030.05
Note: LLOQ values are dependent on sample dilution. These are values for standard methods but can be modified with dilution in case of need.

 

Reproducibility of results

Below are results of measuring a typical hemp sample, followed by an image of stacked 3 consecutive measurements. There are two observations from this measurement:

  1. The retention times are consistent and repeatable, giving the confidence in the ability to correctly identify the correct cannabinoids.
  2. The measured concentrations are very repeatable as indicated by height/area of each peak. The calculated relative standard deviation (RSD) in this case ranges from 1.19% to 1.70%, while for cannabinoids with very low concentrations manifested as very small peaks (in this sample CBN, d9-THC, and d9-THCA) the calculated RSD ranges from 4.62% to 5.63%. In case of need to further refine the latter 3 compounds and improve both accuracy and RSD, the sample would simply be less diluted resulting in higher peaks for these 3 compounds.
Cannabis Testing Simplified CBD sample Cannabis HPLC Analyzer

Cannabis Testing Simplified CBD sample

 

Low CBD repeatability RSD 2 Cannabis HPLC Analyzer

Low CBD repeatability RSD 2 Cannabis HPLC Analyzer

Cannabinoids Testing Process Flow Chart Cannabis HPLC Analyzer

Cannabinoids Testing Process Flow Chart Cannabis HPLC Analyzer

We try to expand the financing options to help our customers acquire the instrument.

Options:

  1. Direct purchase – contact us to get a quote. We accept cryptocurrency transactions.
  2. Financing – we partner with financing firms in cannabis industry to help our customers acquire the instrument. Typical terms are $350 to $500/month. Learn more here.
  3. Rental – contact us for rental terms.

Contact us to get a quote or with any questions.

 

[email protected]

 

Call or Text: +1 (941) 467-8386

WhatsApp: +1 (941) 467-8386